Drosophila

The paper manually traces and analyzes the tracheolar network in the adult Drosophila brain using electron microscopy data, revealing its structure and spatial relationship with neurons.

This study shows that C9orf72 repeat expansions cause presymptomatic lysosomal dysfunction in Drosophila, leading to DPR secretion and neurotoxicity, which can be mitigated by valproic acid.

This study identifies a high-order ion-coupling mechanism in EAAT transporters by showing that dEAAT2 can acquire Na+, H+, and K+ dependence through mutations, mimicking human hEAAT2's complex ion coupling.

The paper examines how Drosophila simulans adapts to three new transposable element invasions through piRNA cluster insertions and finds that resistance evolves independently in different strains.

This study shows that vitamin B3 supplementation protects mitochondria from antibiotic-induced damage, preserving bioenergetics and thermogenesis in Drosophila and human cells.

The paper shows that mesodermal FGF signaling stabilizes the ectoderm during dorsal closure in Drosophila, revealing a reciprocal influence between mesoderm and ectoderm.

The paper introduces PRISM to select low-fidelity simulators for multi-fidelity inference in vertex models, finding that early stopping is unreliable while coarser timesteps are effective.

This study identifies eIF4H1 as a conserved gene regulating sociality and neuronal development in Drosophila, supporting a genetic toolkit for social traits across species.

This study identifies extensive horizontal gene transfer in the fungus gnat Bradysia coprophila, showing these genes contribute to stress tolerance and ecological adaptation.

The paper clusters filopodia dynamics using functional data analysis to identify distinct temporal patterns linked to Notch signaling in fruit fly development.

The paper tests if mitochondrial backgrounds influence nuclear allele fate during hybridization, finding no evidence of such effects despite expected incompatibilities.

This study identifies an internal chemosensory system in Drosophila melanogaster's abdomen using Gustatory Receptors, revealing new roles in interoception beyond traditional feeding behaviors.

The paper investigates how gene expression influences genome-wide mutation rates in Drosophila melanogaster and Caenorhabditis elegans, finding that highly expressed genes have lower mutation rates due to transcription-coupled repair.

This study introduces SOPSim, a simulation tool that models sensory bristle patterning in fruit flies by incorporating filopodia dynamics and Notch signaling.

ORBIS reconstructs 3D tissue geometry from single-cell gene expression without spatial references, achieving lower shape error and faster sampling than existing methods.

This study shows that past adaptation to systemic infection affects the speed and mechanism of adaptation to oral infection in Drosophila, with sex-specific outcomes and trade-offs.

SNAzzy processes and analyzes high-throughput microscopy data from Drosophila embryos to study synchronous network activity.

The paper identifies differences in how two types of descending neurons in hoverflies encode visual information from small targets, revealing distinct pathways for target pursuit and threat detection.

The paper identifies genes under co-evolutionary selection in Drosophila melanogaster by analyzing nucleotide diversity and divergence patterns, finding links to sperm competition and mating behaviors.

The paper reconstructs the asperosaponin biosynthesis pathway in Dipsacus asperoides by integrating genomics, transcriptomics, and biochemical analyses, revealing gene family diversification and glycosylation order.

Earl Grey ParTEA annotates transposable elements across multiple genomes, revealing shared and private TE families and improving annotation consistency.

The paper develops workflows for targeted single-cell and single-nucleus RNA sequencing of rare neural populations in Tribolium castaneum using reporter and antibody-based enrichment strategies.

This study shows that PMCA interacts with Dlg to regulate presynaptic calcium levels in Drosophila NMJ, affecting neurotransmitter release and Ca2+ homeostasis.

The paper shows serotonin signaling spatially controls nutrient-responsive midgut turnover in Drosophila by regulating enteroblast maturation and morphological changes through the 5HT7 receptor.

This study identifies an mTORC1-PWP1-Hedgehog circuit that links nutrient metabolism to intestinal stem cell differentiation in Drosophila, showing its role in aging and tissue renewal.

This study investigates the role of the fruitless P3 transcript in Drosophila development, finding it essential for pupal development and metamorphosis, with distinct effects compared to complete fruitless loss.

This study investigates how larval competition affects gene drive performance in Aedes aegypti mosquitoes using agent-based models and Bayesian optimization.

The paper identifies core brain thermosensors in Drosophila larvae that regulate thermoregulation by modulating the behavioral response to peripheral temperature inputs.

The paper shows microtubules coordinate with actin assembly and disassembly to maintain cortical actin cable elongation in Drosophila nurse cells.

PPI-Rescue restores eye development by reconstituting transcription complexes in Drosophila using targeted mutations and cofactor interactions.