Clair: Exploring the limit of using a deep neural network on pileup data for germline variant calling
Ruibang Luo, Chak-Lim Wong, Yat-Sing Wong, Chi-Ian Tang, Chi-Man Liu, Chi-Ming Leung, Tak‐Wah Lam
Clair is a germline small variant caller using single-molecule sequencing data that achieves high precision, recall, and speed, approaching the accuracy limit for pileup-based deep learning methods.
Nature Machine Intelligence · Apr 6, 2020Peer-reviewedBioinformatics