Estimating Intraclonal Heterogeneity and Subpopulation Changes from Perturbational Bulk Gene Expression Profiles in LINCS L1000 CMap by Premnas
Chiao-Yu Hsieh, Ching-Chih Tu, Jui‐Hung Hung
Premnas estimates subpopulation changes from bulk L1000 profiles in CMap by learning subpopulation representations from single-cell RNA-seq data, enabling new insights into drug responses and resistance.
bioRxiv · Aug 10, 2021 · PreprintBioinformatics