Unsupervised Discovery of Ancestry Informative Markers and Genetic Admixture Proportions in Biobank-Scale Data Sets
Seyoon Ko, Benjamin B. Chu, Daniel Peterson, Chidera Okenwa, Jeanette C. Papp, David H. Alexander, Eric M. Sobel, Hua Zhou, Kenneth L. Lange
This paper introduces an unsupervised framework for selecting ancestry informative markers and estimating admixture proportions in large biobank datasets, demonstrating scalability and effectiveness.
The American Journal of Human Genetics · Jan 6, 2023Peer-reviewedBioinformatics