Critical role of the periplasm in copper homeostasis in Gram-negative bacteria
Jun-ichi Ishihara, Tomohiro Mekubo, Chikako Kusaka, Suguru Kondo, Ryotaro Oiko, Kensuke Igarashi, Hirofumi Aiba, Shu Ishikawa, Naotake Ogasawara, Taku Oshima, Hiroki Takahashi
This study investigates the role of the periplasm and periplasmic proteins in copper homeostasis in Gram-negative bacteria, showing that the periplasm acts as a sensor and storage for copper to adapt to varying environmental concentrations.
Biosystems · Sep 1, 2023Peer-reviewedSystems Biology