Author

Chloe Prosper

Centre Hospitalier Universitaire de Nice

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aleksandra Nadaj‐PaklezaiD· 1 shared Annabelle ChaussenotiD· 1 shared Béatrice Ardin· 1 shared Béatrice LannesiD· 1 shared Bertrand KnebelmanniD· 1 shared Carsten BergmanniD· 1 shared Cécile RouzieriD· 1 shared Claire Goursaud· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Aleksandra Nadaj‐PaklezaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mapping intronic mutational hotspots by in silico mutagenesis enables single antisense oligonucleotide correction of multiple variants

Hassan Saei, Béatrice Ardin, Nicolas Kaiser, Mouad Ouahmane, Olivier Gribouval, Vincent Morinière, Manon Mautret‐Godefroy, Florian J. Wopperer, Korbinian Maria Riedhammer, Daniel Philip Gale, Omid Sadeghi‐Alavijeh, Claire Goursaud, Olivier Grunewald, Chloe Prosper, Louis Lebreton, , Guillaume Dorval

The paper identifies deep intronic mutational hotspots using in silico mutagenesis and demonstrates that a single antisense oligonucleotide can correct multiple variants causing X-linked Alport syndrome.

medRxiv · Sep 15, 2026 · PreprintGenetic & Genomic Medicine

Challenging mtDNA tRNA Variant Guidelines: Emphasizing Single-Cell Analysis through Four Novel Variants

Chloe Prosper, Elamine Zereg, Annabelle Chaussenot, Sylvie Bannwarth, Béatrice Lannes, Nathalie Streichenberger, Elsa Kaphan, Aleksandra Nadaj‐Pakleza, Villa Luisa, Sabrina Sacconi, Marion Masingue, Éléonore Birgy, Francou Bruno, Samira Ait-El-Mkadem, Konstantina Fragaki, , Cécile Rouzier

This study reclassifies four novel mtDNA variants using single-cell NGS analysis, highlighting the need for functional evidence and standardized criteria in variant interpretation.

Mitochondrion · May 17, 2026Peer-reviewedGenetic & Genomic Medicine