Truncation and Motif Based Pan-Cancer Analysis Highlights Novel Tumor Suppressing Kinases.
Andrew M. Hudson, Natalie L. Stephenson, Cynthia Li, Eleanor Trotter, Adam J. Fletcher, Gitta Katona, Patrycja Bieniasz-Krzywiec, Matthew Howell, Chris Wirth, Simon Furney, Crispin J. Miller, John Brognard
The paper identifies novel tumor suppressor kinases using motif-based analysis and functional validation, highlighting the JNK pathway as tumor suppressive in gastric cancer.
bioRxiv · Jan 27, 2018 · PreprintCancer Biology