Principles of protein abundance regulation across single cells in a mammalian tissue
Andrew Leduc, Gergana G. Shipkovenska, Yanxin Xu, Christina Jiang, Alexander M. Franks, Nikolai Slavov
The paper quantifies protein synthesis and clearance across 4,200 cells, revealing that translation and clearance are linearly dependent on growth rate and identifying cell-type specific regulatory mechanisms.
bioRxiv · Sep 17, 2025 · PreprintCell Biology