Genome-wide expression gradient estimation based on local pseudotime in single cell RNA sequencing
Andreas Tjärnberg, Christopher A Jackson, Lionel Christiaen, Richard Bonneau
The paper introduces pseudovelocity, a method to estimate gene-specific RNA velocity using kNN-G and diffusion-based pseudotime, improving gene-based velocity estimation for downstream analysis.
bioRxiv · May 1, 2025 · PreprintBioinformatics