Scaled Testosterone: A Novel Metric to Calibrate Serum Testosterone and SHBG in Men
David J. Handelsman, Gary Wittert, Bu Beng Yeap, CM Muir, PhD Leon Flicker MBBS, Mark Ng Tang Fui, Mathis Grossmann
The paper introduces a novel metric, Scaled Testosterone (ST), to assess serum testosterone and SHBG in men, showing it can distinguish between true hypogonadism and obesity-related pseudo-hypogonadism.
bioRxiv · May 27, 2026 · PreprintPhysiology