Inferring causal cell types of human diseases and risk variants from candidate regulatory elements
Artem Kim, Zixuan Zhang, Come Legros, Hongbo Wang, Zeyun Lu, Adam J. de Smith, Jill E. Moore, Arun Durvasula, Nicholas Mancuso, Steven Gazal
This paper introduces CT-FM and CT-FM-SNP methods to identify causal cell types and variants for diseases, finding most SNPs affect traits via a single cell type set.
Cell Genomics · Aug 14, 2026Peer-reviewedGenetic & Genomic Medicine