Canonical mTOR signaling supports complete fin regeneration
Josane F. Sousa, Gabriela Lima, Louise Perez, Michaela Tsanova, Cyrus Bronson, Garrison Boehl, Icyss Sargeant, Rogerio Gomes, Aline Cutrim Dragalzew, Wainna Renata Barroso Mendes, Igor Schneider
This study shows that canonical mTOR signaling supports fin regeneration in Polypterus senegalus, challenging the idea that hypersensitive mTOR is required for complex appendage regeneration.
bioRxiv · Mar 30, 2026 · PreprintDevelopmental Biology