Neutral vs. non-neutral genetic footprints of Plasmodium falciparum multiclonal infections
F. Labbe, Q. He, Q. Zhan, K. E. Tiedje, D. C. Argyropoulos, M. H. Tan, A. Ghansah, K. P. Day, M. Pascual
This paper compares two methods for estimating malaria parasite multiplicity of infection under different transmission intensities, finding that varcoding is more robust in high-transmission settings while THE REAL McCOIL performs better in low-to-moderate transmission.
bioRxiv · Jun 27, 2022Evolutionary Biology