Author

D. Riccardi

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Biophysics· 1

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Approach:simulation· 1

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L. Pegram· 1 shared N. G. Ahn· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiophysics

L. Pegram

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1 paper

Recent·Most cited

Activation loop plasticity and active site coupling in the MAP kinase, ERK2

L. Pegram, D. Riccardi, N. G. Ahn

This study uses molecular dynamics simulations to show that the A-loop in ERK2 adopts multiple conformational states linked to active site dynamics, revealing allosteric coupling between the activation loop and catalytic site.

bioRxiv · Apr 15, 2023Biophysics