Author

Da-Inn Lee

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Approach:matrix factorization· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Sushmita RoyiD· 2 shared

Activity by Year

2021-2023 · peak 1/yr

2 papers

Recent·Most cited

Examining dynamics of three-dimensional genome organization with multi-task matrix factorization

Da-Inn Lee, Sushmita Roy

This paper introduces TGIF, a multi-task NMF method for analyzing 3D genome dynamics across Hi-C datasets, identifying structural changes linked to regulatory signals and gene expression.

bioRxiv · Aug 25, 2023 · PreprintBioinformatics

Simultaneous smoothing and detection of topological units of genome organization from sparse chromatin contact count matrices with matrix factorization

Da-Inn Lee, Sushmita Roy

GRiNCH identifies and smooths topological units from sparse chromatin contact data, improving TAD detection and structural recovery across different sequencing depths.

Genome biology · May 25, 2021Peer-reviewedBioinformatics