MutaStruct: Revisiting Benchmarks for Single-Site Mutation-Induced Structural Change Prediction
Huynh Tan-Phat, Dang-Manh Ho, Viet Thanh Duy Nguyen, Quang-Hien Kha, Ngoc-Thac Pham, Kuei-Hung Lai, Truong Son Hy
The paper introduces MutaStruct, a curated benchmark for evaluating mutation-induced structural changes, showing that overall structural fidelity does not guarantee accurate modeling of mutation effects.
bioRxiv · Oct 22, 2026 · PreprintBioinformatics