Effective gene expression prediction from sequence by integrating long-range interactions
Žiga Avsec, Vikram Agarwal, Daniel Visentin, Joseph R. E. Ledsam, Agnieszka Grabska‐Barwińska, Kyle R. Taylor, Yannis Assael, John Jumper, Pushmeet Kohli, David R. Kelley
Enformer, a sequence-based transformer integrating elements up to 100 kb away, lifts held-out gene expression prediction (correlation 0.81 to 0.85 versus Basenji2) and variant effect prediction.
Nature Methods · Oct 1, 2021Peer-reviewedGenomics✦ In-depth digest