Prevalence of Pathogenic Germline Variants in Cancer Susceptibility Genes using the All of Us Dataset
Gideon Idumah, Daphne Newell, Madeleine Hadrys, Isabella Ribaudo, Ying Ni, Joshua Arbesman
The paper analyzes pathogenic germline variants in cancer susceptibility genes across a large population using the All of Us dataset, finding 5.05% prevalence with significant racial variation.
medRxiv · Mar 28, 2025 · PreprintGenetic & Genomic Medicine