Sexual dimorphism of complement-dependent microglial synaptic pruning and other immune pathways in the developing brain
Daria Prilutsky, Alvin T. Kho, Ariel Feiglin, Timothy Hammond, Beth Stevens, Isaac S. Kohane
The paper identifies sex-specific differences in immune-related pathways, particularly complement-dependent microglial synaptic pruning, during brain development and suggests their role in sex differences in neurological disorder vulnerability.
bioRxiv · Dec 29, 2017 · PreprintNeuroscience