Author

Dave Estell

International Flavors & Fragrances (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Aalt D. J. van DijkiD· 1 shared Dick de RidderiD· 1 shared Diego Staphorst· 1 shared Floris J. van der FlieriD· 1 shared Frits Goedegebuur· 1 shared Harm Mulder· 1 shared Henning RedestigiD· 1 shared Laurens Lammerts· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Aalt D. J. van DijkORCID

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1 paper

Recent·Most cited

Enzyme structure correlates with variant effect predictability

Floris J. van der Flier, Dave Estell, Sina Pricelius, Lydia Dankmeyer, Sander van Stigt Thans, Harm Mulder, Rei Otsuka, Frits Goedegebuur, Laurens Lammerts, Diego Staphorst, Aalt D. J. van Dijk, Dick de Ridder, Henning Redestig

The paper shows that structural features of enzymes influence the predictability of variant effects, with consistent dependencies across multiple models.

Computational and Structural Biotechnology Journal · Oct 2, 2024Peer-reviewedBioinformatics