The covariance shift (C-SHIFT) algorithm for normalizing biological data
Evgenia Chunikhina, Paul Logan, Yevgeniy Kovchegov, Anatoly Yambartsev, Debashis Mondal, Andrey Morgun
The paper introduces the C-SHIFT normalization method to recover the covariance matrix from gene expression data by minimizing noise and improving accuracy over existing techniques.
bioRxiv · Apr 13, 2020 · PreprintBioinformatics