STAT3 promotes RNA polymerase III-directed transcription by controlling the miR-106a-5p/TP73 axis
Cheng Zhang, Shasha Zhao, Huan Deng, Shihua Zhang, Juan Wang, Xiaoye Song, Deen Yu, Yue Zhang, Wensheng Deng
This study identifies STAT3 as a positive regulator of RNA polymerase III transcription through the miR-106a-5p/TP73 axis, showing STAT3 inhibits TP73 and miR-106a-5p activates Pol III transcription.
eLife · Jan 6, 2023Peer-reviewedMolecular Biology