Author

Demi Zhuang

Columbia University Irving Medical Center

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Bioinformatics· 1

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Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Guojie ZhongiD· 1 shared Wendy K. ChungiD· 1 shared Yige ZhaoiD· 1 shared Yufeng SheniD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBioinformatics

Guojie ZhongORCID

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1 paper

Recent·Most cited

PreMode predicts mode-of-action of missense variants by deep graph representation learning of protein sequence and structural context

Guojie Zhong, Yige Zhao, Demi Zhuang, Wendy K. Chung, Yufeng Shen

PreMode predicts the mode-of-action of missense variants using graph neural networks, achieving state-of-the-art performance in mode-of-action classification.

Nature Communications · Aug 5, 2025Peer-reviewedBioinformatics