Host Metabolic Reprogramming Defines Macrophage Antifungal Activity Against Cryptococcus neoformans
Ayesha S. Nair, Dikshanta V. Luitel, Karen L. Wozniak
The paper investigates how metabolic reprogramming in macrophages affects antifungal activity against Cryptococcus neoformans, finding that glycolytic metabolism is enhanced in antifungal cells while mitochondrial and anabolic pathways are reduced.
bioRxiv · Oct 7, 2026 · PreprintImmunology