Profiling of Aggregated Amyloid β42-induced Proteomic Alterations in KOLF2.1J Induced Pluripotent Stem Cell-derived Neurons
Benjamin Jin, Ziyi Li, Ying Hao, Isabelle Kowal, Jacob Epstein, Marianita Santiana, Cory A. Weller, Mike A. Nalls, Dingying Tao, 方圣云, Priyanka S. Narayan, Andrew Singleton, Kendall R. Van Keuren‐Jensen, Luigi Ferrucci, Michael E. Ward, , Yue Andy Qi
This study profiles proteomic changes in iPSC-derived neurons exposed to Aβ42A, revealing AD-related pathways and validating findings in postmortem AD brain tissue.
bioRxiv · Sep 25, 2026 · PreprintNeuroscience