Information-dependent Enrichment Analysis Reveals Time-dependent Transcriptional Regulation of the Estrogen Pathway of Toxicity
Salil N. Pendse, Alexandra Maertens, Michael Rosenberg, Dipanwita Roy, Rick A. Fasani, Marguerite M. Vantangoli, Samantha J. Madnick, Kim Boekelheide, Albert J. Fornace, James D. Yager, Thomas Hartung, Melvin E. Andersen, Patrick D. McMullen
This paper introduces IDEA, a novel enrichment analysis method to identify transcription factor networks involved in estrogen pathway toxicity, showing improved performance over existing methods.
bioRxiv · Feb 4, 2016Bioinformatics