Association of HOXB13 G84E with prostate cancer among 592,158 men
Taylor B. Crawford, Tyler J. Nelson, Roshan A. Karunamuni, Heena Desai, Ryan M. Hausler, Craig Carl Teerlink, Hannah K. Carter, Meghana S. Pagadala, Patrick R. Alba, Scott L. DuVall, Morgan E. Danowski, Charles A. Brunette, Dmitry Ratner, Isla P. Garraway, Brent Shane Rose, , Kara N. Maxwell
This paper shows the HOXB13 p.G84E variant increases prostate cancer risk by threefold in men, but does not lead to more aggressive cancer.
Journal of the National Comprehensive Cancer Network · Sep 15, 2025Peer-reviewedGenetic & Genomic Medicine