Identification Of cis-Regulatory Mutations Generating De Novo Edges In Personalized Cancer Gene Regulatory Networks
Zeynep Kalender Atak, Hana Imrichová, Dmitry Svetlichnyy, Gert J. Hulselmans, Valerie Christiaens, Joke Reumers, Hugo Ceulemans, Stein Aerts
The paper introduces a computational pipeline, cisTarget, to identify functional non-coding mutations in cancer genomes by analyzing their impact on personalized gene regulatory networks.
Genome Medicine · Aug 30, 2017Peer-reviewedGenomics