Author

Domitilla Del Vecchio

Primary ORCID profile (0000-0001-6472-8576 · 24 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Domitilla Del VecchioiD24 papers · Massachusetts Institute of Technology

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:simulation· 1

Frequent Co-Authors

Fiona A Chandra· 1 shared Shaoshuai Mou· 1 shared

Activity by Year

2016-2016 · peak 2/yr

Co-Author Collaboration Network

2 top collaborators · 0 mutual co-author links

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1 shared paperSystems Biology

Fiona A Chandra

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2 papers

Recent·Most cited

The Effects of Ribosome Autocatalysis and Negative Feedback in Resource Competition

Fiona A Chandra, Domitilla Del Vecchio

This study models ribosome and protein synthesis with autocatalysis and feedback to show how these factors affect system stability and transient behavior under increased ribosome demand.

bioRxiv · Mar 4, 2016 · PreprintSystems Biology

Transcription factor loads tend to decrease the robustness of stable gene transcription networks

Shaoshuai Mou, Domitilla Del Vecchio

The paper shows that transcription factor loads reduce the robustness of stable gene transcription networks by shrinking the parameter space where circuits function correctly.

bioRxiv · Jan 21, 2016 · PreprintSystems Biology