Author

Doreen Klingler

Universitätsklinikum Tübingen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:scRNA-seq· 1 Research Focus:software / tool· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Jan T. SchleicheriD· 2 shared Manfred ClaasseniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Jan T. SchleicherORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Accurate quantification of spliced and unspliced transcripts for single-cell RNA sequencing with tidesurf

Jan T. Schleicher, Doreen Klingler, Manfred Claassen

The paper introduces tidesurf, a tool for quantifying spliced and unspliced transcripts in scRNA-seq, showing improved accuracy over velocyto for 5' chemistry data.

PLoS ONE · Aug 17, 2026Peer-reviewedBioinformatics

Quantification of spliced and unspliced transcripts by velocyto is inaccurate for 5'-sequencing data

Doreen Klingler, Jan T. Schleicher, Manfred Claassen

This study shows that velocyto inaccurately quantifies spliced and unspliced transcripts for 5'-sequencing data, leading to incorrect velocity predictions.

bioRxiv · Jan 17, 2025 · PreprintBioinformatics