Are carbohydrate ring distortions determined by biology or crystallography? The impact of experimental conditions on structural data
Douglas Silva Lima, Vinícius Cabral, Hugo Verli
This study analyzes carbohydrate structures in the PDB to assess the impact of experimental conditions on their conformation, finding that non-chair conformations are rare even with increased CryoEM data.
bioRxiv · Oct 6, 2026 · PreprintBiophysics