Promoter-Enhancer Interactions Identified from Hi-C Data using Probabilistic Models and Hierarchical Topological Domains
Gil Ron, Yuval Globerson, Dror Moran, Tommy Kaplan
The paper introduces PSYCHIC, a method to identify promoter-enhancer interactions from Hi-C data, revealing extensive gene regulation catalogs in human and mouse.
Nature Communications · Dec 15, 2017Peer-reviewedBioinformatics