How different AI models understand cells differently
Yubo Zhao, Duozhi Sun, Minsheng Hao, Yifan Xiong, Chen Li, Tieliang Gong, Lei Wei, Xuegong Zhang
This paper introduces scGeneLens, a framework to analyze how different AI models perceive cells, revealing that scFoundation focuses on cell-type markers while scGPT emphasizes shared pathways.
bioRxiv · Jan 30, 2026 · PreprintBioinformatics