A susceptibility locus on chromosome 13 profoundly impacts the stability of genomic imprinting in mouse pluripotent stem cells
E. Swanzey, T. F. McNamara, E. Apostolou, M. Tahiliani, M. Stadtfeld
This study identifies a genetic locus on chromosome 13 that influences epigenetic stability in mouse pluripotent stem cells and shows that ascorbic acid can prevent loss-of-imprinting.
bioRxiv · Jan 25, 2020Cell Biology