Modulation of multiple gene clusters expression by a single PAS-LuxR transcriptional regulator
C. M. Vicente, T. D. Payero, A. Rodríguez-García, E. G. Barreales, A. de Pedro, F. Santos-Beneit, J. F. Aparicio
This study shows that PteF, a PAS-LuxR regulator in Streptomyces avermitilis, negatively modulates multiple gene clusters, including those for secondary metabolites, despite being an activator of filipin biosynthesis.
bioRxiv · Jun 10, 2022 · PreprintMicrobiology