Heterogeneity of circulating epithelial cells in breast cancer at single-cell resolution: identifying tumor and hybrid cells
M. E. Menyailo, V. R. Zainullina, L. A. Tashireva, S. Y. Zolotareva, T. S. Gerashchenko, V. V. Alifanov, O. E. Savelieva, E. S. Grigoryeva, N. A. Tarabanovskaya, N. O. Popova, A. A. Khozyainova, E. L. Choinzonov, N. V. Cherdyntseva, V. M. Perelmuter, E. V. Denisov
This study uses single-cell RNA sequencing to analyze circulating epithelial cells in breast cancer patients, identifying tumor and hybrid cells based on DNA ploidy and functional characteristics.
bioRxiv · Nov 24, 2021Cancer Biology