Epistasis within the MHC contributes to the genetic architecture of celiac disease
Benjamin Goudey, Gad Abraham, Eder Kikianty, Qiao Wang, Dave Rawlinson, Fan Shi, Izhak Haviv, Linda Stern, Adam Kowalczyk, Michael Inouye
This study identifies epistatic interactions within the MHC region that contribute to celiac disease risk, finding 20 significant signals independent of known HLA haplotypes.
bioRxiv · Aug 11, 2015 · PreprintGenomics