Study on the mechanism of action of the Pt(IV) complex with lonidamine ligands by ultrafast chemical proteomics
Ekaterina A.. Imaikina, Ivan I. Fedorov, Daria D. Emekeeva, Elizaveta M. Kazakova, Leyla A. Garibova, Mark V. Ivanov, Ilya A. Shutkov, Alexey A. Nazarov, Mikhail V. Gorshkov, Irina A. Tarasova
This study investigates the mechanism of action of a Pt(IV) complex with lonidamine ligands using chemical proteomics in ovarian cancer cells, revealing its impact on glucose metabolism.
ACS Pharmacology & Translational Science · Mar 28, 2025Peer-reviewedPharmacology & Toxicology