Endothelial Cell SMAD6 Balances ACVRL1/Alk1 Function to Regulate Adherens Junctions and Hepatic Vascular Development
Molly R. Kulikauskas, Morgan Oatley, Tianji Yu, Ziqing Liu, Lauren Matsumura, Elise Kidder, Dana L. Ruter, Victoria L. Bautch
This study shows SMAD6 in endothelial cells balances ALK1 signaling to regulate vascular development and junction integrity, preventing hemorrhage and vascular defects in the embryonic liver.
Development · Oct 3, 2023Peer-reviewedDevelopmental Biology