Author

Elizabeth Ing-Simmons

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:multiple species· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Boris Lenhard· 1 shared Ge Tan· 1 shared Malcolm Perry· 1 shared Matthias Merkenschlager· 1 shared Nathan Harmston· 1 shared

Activity by Year

2016-2016 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperGenomics

Boris Lenhard

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1 paper

Recent·Most cited

Topologically associated domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation

Nathan Harmston, Elizabeth Ing-Simmons, Ge Tan, Malcolm Perry, Matthias Merkenschlager, Boris Lenhard

The paper shows that genomic regulatory blocks (GRBs) align with topologically associating domains (TADs) in metazoan genomes, suggesting ancient, conserved structures involved in developmental regulation.

bioRxiv · Aug 28, 2016 · PreprintGenomics