Author

Elizabeth Purdom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Marla Johnson· 2 shared Sean Ruddy· 1 shared

Activity by Year

2015-2015 · peak 2/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersBioinformatics

Marla Johnson

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2 papers

Recent·Most cited

Clustering of mRNA-Seq data for detection of alternative splicing patterns

Marla Johnson, Elizabeth Purdom

The paper introduces a method to cluster mRNA-Seq data based on isoform usage rather than gene expression levels, showing improved sensitivity in detecting alternative splicing patterns.

bioRxiv · Jun 30, 2015 · PreprintBioinformatics

Shrinkage of dispersion parameters in the binomial family, with application to differential exon skipping

Sean Ruddy, Marla Johnson, Elizabeth Purdom

The paper introduces a shrinkage method for dispersion parameters in a binomial model to detect differential exon skipping in mRNA-Seq data, showing it is fast, powerful, and controls FDR well.

bioRxiv · Jun 22, 2015Bioinformatics