Association mapping reveals the role of mutation-selection balance in the maintenance of genomic variation for gene expression.
Emily B. Josephs, Young Wha Lee, John R. Stinchcombe, Stephen I. Wright
The paper tests mutation-selection balance theory by analyzing eQTLs and aseQTLs in Capsella grandiflora, finding rare alleles with negative frequency-effect size correlations.
bioRxiv · Sep 21, 2015Evolutionary Biology