Predicting localized affinity of RNA binding proteins to transcripts with convolutional neural networks
Alexander Kitaygorodsky, Emily Jin, Yufeng Shen
The paper introduces POLARIS, a deep-learning method for predicting localized RBP binding affinity to transcripts, achieving high performance across cell lines and enabling interpretation of noncoding variants.
bioRxiv · Jun 2, 2021 · PreprintBioinformatics