A Pan-Cancer Transcriptome Analysis Reveals Pervasive Regulation through Tumor-Associated Alternative Promoters
Deniz Demircioğlu, Martin Kindermans, Tannistha Nandi, Engin Cukuroglu, Claudia Calabrese, Nuno A. Fonseca, André Kahles, Kjong-Van Lehmann, Oliver Stegle, Alvis Brāzma, Angela Norie Brooks, Gunnar Rätsch, Patrick B. O. Tan, Jonathan Göke, and the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network on behalf of the PCAWG Transcriptome Working Group
This study identifies alternative promoters as key regulators in the cancer transcriptome using RNA-Seq data from 1,188 cancer samples.
Cell · Sep 1, 2019Peer-reviewedGenomics