Constructed Negatives Shape the Evaluation of Sequence-Based Protein--Protein Interaction Models
Enzo Durand, Sergei Grudinin, Béatrice Durand, Élodie Laine
The paper evaluates how different constructed negative examples affect sequence-based protein-protein interaction models, showing significant variability in performance metrics based on negative construction methods.
bioRxiv · Oct 15, 2026 · PreprintBioinformatics