In Vitro Assay for the Detection of Network Connectivity in Embryonic Stem Cell-Derived Cultures
Jeffrey R Gamble, Eric T Zhang, Nisha Iyer, Shelly Sakiyama-Elbert, Dennis L Barbour
This study develops an in vitro assay to assess network connectivity in ESC-derived neuronal cultures using MEAs and connectivity detection algorithms, finding that aggregated cultures show spatiotemporal connectivity patterns similar to in vivo tissue.
bioRxiv · Jul 26, 2018 · PreprintBioengineering