Long-term Effects of Early Life Adversity On Brain Dopamine and Serotonin Receptor Systems Involved In Cocaine Reinforcement In Adult Macaques: a Positron Emission Tomography study
Jose Acevedo-Polo, Erin R. Siebert, Jessica Khan, Mia I Rough, Ronald J. Voll, Lahu N. Chavan, Mark M. Goodman, Jonathon A. Nye, Michael A. Nader, M. Mar Sánchez
This study investigates the long-term effects of early life adversity on serotonin and dopamine receptor systems in adult macaques, finding persistent 5HT receptor changes and associations with cocaine self-administration outcomes.
bioRxiv · Jan 20, 2026 · PreprintNeuroscience