Present-day admixed genomes reveal prehistoric adaptation to cold, maritime diet, and local pathogens in Patagonia
Patricio Pezo, Michael Orellana‐Soto, Alexandra Salcedo, Juan Esteban Rodríguez-Rodríguez, Cristian Matus Yañez, Elena Llop, Eugenio Aspillaga, María Laura Parolín, Andrés Moreno‐Estrada, Carlos D. Bustamante, Julian R. Homburger, Christopher R. Gignoux, Alexander G. Ioannidis, Celeste S. Eng, Scott Huntsman, , Ricardo A. Verdugo
The paper analyzes genome-wide data from Indigenous Patagonians to uncover genetic adaptations to cold, maritime diet, and pathogens, revealing prehistoric selection signals and admixture patterns.
medRxiv · Aug 21, 2025 · PreprintGenetic & Genomic Medicine