The combination of the functionalities of feedback circuits is determinant for the number and size of attractors of molecular networks
Eugenio Azpeitia, Stalin Munoz, Daniel Gonzalez-Tokman, Mariana Esther Martinez-Sanchez, Nathan Weinstein, Aurelien Naldi, Elena ER Alvarez-Buylla, David A Rosenblueth, Luis Mendoza
The paper shows that the combination of feedback circuit functionalities determines the number and size of attractors in molecular networks, affecting epistasis analysis results.
bioRxiv · Jun 24, 2016Systems Biology