HERCULES: a deep-learning framework for RNA-binding region localization and mutation-effect prediction
Jonathan Fiorentino, Michele Monti, Alexandros Armaos, Dimitrios Miltiadis Vrachnos, Lorenzo Di Rienzo, Veronica Venturi, Maria Teresa Botta Orfila, Eulalia Marti Puig, Gian Gaetano Tartaglia
HERCULES predicts RNA-binding regions and mutation effects using a deep-learning framework combining language models and physicochemical descriptors.
bioRxiv · Oct 27, 2026 · PreprintBiochemistry